Domperidone cardiovascular risk

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Domperidone cardiovascular risk

Posted Apr 26, 2016 by Admin

Information for consumers This monitoring communication highlights a potential safety concern. For most people, taking domperidone is safe. However, if you have existing heart problems, check with your health professional to make sure that this medicine is appropriate for you. The TGA is reviewing new information regarding domperidone (Motilium) and its potential effects on the patient's heart, particularly with doses above 30 mg daily. Domperidone is a medicine used for relief of symptoms of nausea and vomiting, and delayed stomach emptying.

Patients with underlying cardiovascular risk factors may be at higher risk, including people taking any medicines known to prolong the QT interval. Domperidone should not be used with medicines that prolong QT interval or with medicines that inhibit CYP3A4.

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If you experience any symptoms that could be caused by abnormal heart rhythms, including dizziness, fainting or heart palpitations, stop taking domperidone and seek medical attention. If you have any questions or concerns about this issue, speak to your health professional.

Domperidone a new dopamine antagonist

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Information for health professionals Domperidone should be used at the lowest effective dose for the shortest time possible. Discuss the benefits and risks of domperidone treatment with patients who are taking, or for whom you may prescribe, this medicine.

Reporting problems. In addition to adverse events involving domperidone, consumers and health professionals are encouraged to report all problems with medicines or vaccines. Your report will contribute to the TGA's monitoring of these products.

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