Simultaneous estimation of cinnarizine and domperidone

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Simultaneous estimation of cinnarizine and domperidone

Posted Apr 28, 2016 by Admin

In dual wavelength method, two wavelengths were selected for each drug in a way so that the difference in absorbance is zero for another drug. Domperidone shows equal absorbance at 240.2 nm and 273.2 nm, where the differences in absorbance were measured for the determination of Cinnarizine.The suggested methods were validated as per USP guidelines and the results revealed that they are reliable, reproducible and precise for routine use with short analysis time. The results obtained by the proposed methods were statistically compared to the reported method, and there was no. Journal of Pharmaceutical and Scientific. FOR SIMULTANEOUS ESTIMATION OF CINNARIZINE. for simultaneous estimation of Cinnarizine and Domperidone in.

Journal of Pharmaceutical and Biomedical Analysis. Volume 30, Issue 1, Pages 2133. Department of Analytical Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini, 11562 Cairo, Egypt. This work is concerned with the simultaneous determination of domperidone maleate (DOM) and cinnarizine (CINN ) in a binary.The first method is the application of derivative ratio spectrophotometry where the linearity range was 2.530 g/ml, 2.525 g/ml for DOM and CINN, respectively, and percentage recoveries were and for DOM and CINN, respectively, in their laboratory prepared mixtures.

Similarly, differences in absorbance at 230.8 nm and 259.2 nm were measured for determination of Domperidone. The proposed methods were applied for determination of Cinnarizine and Domperidone over the concentration ranges of 220 and 222 g mL1, respectively.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. Volume 113, September 2013, Pages 291296 Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Bani-Suef University, Alshaheed Shehata Ahmad Hegazy St., 62111 Beni-Suef, Egypt.

New spectrophotometric determination of Cinnarizine and Domperidone. Area under curve method is simple with minimal sample and data manipulation. Dual wavelength method can resolve binary mixture with overlapping spectra. The proposed methods are more sensitive and selective than the published methods.DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF CINNARIZINE AND DOMPERIDONE. Simultaneous Estimation of Cinnarizine.

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Home » development and validation of spectrophotometric method for simultaneous estimation of cinnarizine and domperidone maleate in pure and tablet dosage form.Simultaneous estimation of cinnarizine and domperidone by high performance thin layer. Simultaneous estimation of cinnarizine and domperidone by high.

All rights reserved. No articles found. This article has not been cited. Help Help.For the AUC method, the area under curve of mixture solutions in the wavelength ranges 241258 nm and 280292 nm were selected for determination of Cinnarizine and Domperidone and by applying Cramers rule, concentration of each drug was obtained.

Graphical abstract Keywords Spectrophotometry; Cinnarizine; Domperidone; Area under curve; Dual wavelength; Pharmaceutical formulation Copyright 2013 Elsevier B.V. All rights reserved. No articles found. This article has not been cited. Help Help.Principle component analysis followed by a regression step 39. The aim of this paper was to investigate the possibility of using derivative spectrophotometry and.

Simultaneous determination of Cinnarizine and Domperidone by area under curve and dual wavelength spectrophotometric methods on DeepDyve. determination of.Accurate, selective and sensitive spectrophotometric methods have been developed and validated for simultaneous determination of Cinnarizine and Domperidone, a binary mixture with overlapping spectra, without preliminary separation. These methods include area under the curve (AUC) and dual wavelength spectrophotometry.

Simultaneous Estimation and Development of UV Spectroscopic Method for Determination of Cinnarizine and Domperidone. cinnarizine and domperidone by simultaneous.Publication » Simultaneous estimation of Cinnarizine and Domperidone maleate in tablets by reverse phase HPLC.

Simultaneous determination of Cinnarizine and Domperidone by area under curve and dual wavelength spectrophotometric methods. Maha M. Abdelrahman.And Canada only Estimated shipping time is 21days See Pharmacy Profile Go To Pharmacy Your Safety " PharmacyChecker Approved " means: Pharmacy is licensed Prescription is required Pharmacy contact information is confirmed Privacy policies protect personal information Personal/financial data transmission is encrypted 100 0.15 24.99.